| Minerva Med 1992 Mar;83(3):135-9
Chronic use of glucomannan
in the dietary treatment of severe obesity
[Article in Italian]
Vita PM, Restelli A, Caspani P, Klinger R.
Centro per la Farmacoterapia delle Malattie Nutrizionali, Universita
degli Studi di Milano.
Two groups of 25 severely obese patients underwent 3 months
of hypocaloric diet therapy either alone or associated with
a glucomannan-based fibrous diet supplement (approx. 4 g/die
in 3 doses). The comparative analysis of the results obtained
in both groups showed that the diet + glucomannan group had
a more significant weight loss in relation to the fatty mass
alone, an overall improvement in lipid status and carbohydrate
tolerance, and a greater adherence to the diet in the absence
of any relevant side effects. Due to the marked ability to satiate
patients and the positive metabolic effects, glucomannan diet
supplements have been found to be particularly efficacious and
well tolerated even in the long-term treatment of severe obesity.
- Clinical Trial
- Randomized Controlled Trial